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Colchicine glycorandomization influences cytotoxicity and mechanism of actionAHMED, Aqeel; PETERS, Noël R; FITZGERALD, Megan K et al.Journal of the American Chemical Society. 2006, Vol 128, Num 44, pp 14224-14225, issn 0002-7863, 2 p.Article

7,11-epi-thyrsiferol : Completion of its synthesis, evaluation of its antimitotic properties, and the further development of an SAR modelNISHIGUCHI, Gisele A; GRAHAM, John; BOURAOUI, A et al.Journal of organic chemistry. 2006, Vol 71, Num 16, pp 5936-5941, issn 0022-3263, 6 p.Article

QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIPS OF COLCHICINES AGAINST P388 LEUKEMIA IN MICEQUINN FR; BEISLER JA.1981; J. MED. CHEM.; ISSN 0022-2623; USA; DA. 1981; VOL. 24; NO 3; PP. 251-256; BIBL. 27 REF.Article

A NEW APPROACH TO THE SYNTHESIS OF TROPOLONES: SYNTHESES OF COLCHICINE AND BETA -DOLABRIN.EVANS DA; HART DJ; KOELSCH PM et al.1978; J. AMER. CHEM. SOC.; U.S.A.; DA. 1978; VOL. 100; NO 14; PP. 4593-4594; BIBL. 15 REF.Article

Syntheses and biological evaluation of ring-C modified colchicine analogsBAIYUAN YANG; ZHU, Zhiqing C; GOODSON, Holly V et al.Bioorganic & medicinal chemistry letters (Print). 2010, Vol 20, Num 12, pp 3831-3833, issn 0960-894X, 3 p.Article

Synthesis and biological evaluation of novel anticancer bivalent colchicine―tubulizine hybridsMALYSHEVA, Yulia B; COMBES, Sebastien; ALLEGRO, Diane et al.Bioorganic & medicinal chemistry. 2012, Vol 20, Num 14, pp 4271-4278, issn 0968-0896, 8 p.Article

Syntheses of colchicine and isolchicine labelled with carbon-11 or carbon-13KOTHARI, P. J; FINN, R. D; LARSON, S. M et al.Journal of labelled compounds & radiopharmaceuticals. 1995, Vol 36, Num 6, pp 521-528, issn 0362-4803Article

Antitumor agents. CXXXI: Synthesis and biological evaluation of novel thiocolchicine analogs : N-acyl-, N-aroyl-, and N-(substituted benzyl)deacetylthiocolchicines as potent cytotoxic and antimitotic compoundsLI SUN; HAMEL, E; LIN, C. M et al.Journal of medicinal chemistry (Print). 1993, Vol 36, Num 10, pp 1474-1479, issn 0022-2623Article

Structures of tetra-O-demethylcolchicine, -isocolchicine, and 10-O-demethylcolchicine derivativesKASHIWADA, Y; SUN, L; TATEMATSU, H et al.Heterocycles (Sendai). 1993, Vol 36, Num 11, pp 2531-2540, issn 0385-5414Article

Synthèse de conjugués 1,1 gem-bisphosphoniques de la déacétylthiocolchicine et de son dérivé obtenu par réarrangement de Demjanov = Synthesis of 1,1-gembisphosphonic conjugates of deacethylthiocolchicine and the analog prepared by Demjanov rearrangementMauguen Ronan; Sturtz, Georges.1996, 152 p.Thesis

A CONVERGENT TOTAL SYNTHESIS OF ( +OU- )-COLCHICINE AND ( +OU- )-DESACETAMIDOISOCOLCHICINEEVANS DA; TANIS SP; HART DJ et al.1981; J. AM. CHEM. SOC.; ISSN 0002-7863; USA; DA. 1981; VOL. 103; NO 19; PP. 5813-5821; BIBL. 32 REF.Article

BIOLOGICAL EFFECTS OF MODIFIED COLCHICINES. IMPROVED PREPARATION OF 2-DEMETHYLCOLCHICINE, 3-DEMETHYLCOLCHICINE, AND (+)-COLCHICINE AND REASSIGNMENT OF THE POSITION OF THE DOUBLE BOND IN DEHYDRO-7-DEACETAMIDOCOLCHICINESROESNER M; CAPRARO HG; JACOBSON AE et al.1981; J. MED. CHEM.; ISSN 0022-2623; USA; DA. 1981; VOL. 24; NO 3; PP. 257-261; BIBL. 34 REF.Article

TRANSPOSITION BENZENOIDE DE LA COLCHICINE SOUS L'EFFET DE L'ETHYLENEGLYCOLKISELEV VV; PEREL'SON ME; KIKOT BS et al.1977; ZH. ORG. KHIM.; S.S.S.R.; DA. 1977; VOL. 13; NO 11; PP. 2337-2342; BIBL. 8 REF.Article

Antitumor agents 273. Design and synthesis of N-alkyl-thiocolchicinoids as potential antitumor agentsKOZAKA, Takashi; NAKAGAWA-GOTO, Kyoko; QIAN SHI et al.Bioorganic & medicinal chemistry letters (Print). 2010, Vol 20, Num 14, pp 4091-4094, issn 0960-894X, 4 p.Article

Synthesis, photochemical reactions, and tubulin binding of novel photoaffinity labeling derivatives of colchicineSTARETZ, M. E; HASTIE, S. B.Journal of organic chemistry. 1993, Vol 58, Num 6, pp 1589-1592, issn 0022-3263Article

Synthesis and biological evaluation of 2-substituted-4-(3',4',5'-trimethoxy-phenyl)-5-aryl thiazoles as anticancer agentsROMAGNOLI, Romeo; GIOVANNI BARALDI, Pier; BASSO, Giuseppe et al.Bioorganic & medicinal chemistry. 2012, Vol 20, Num 24, pp 7083-7094, issn 0968-0896, 12 p.Article

Synthesis of 14C labelled electrophilic ligands of the colchicine binding site of tubulin : chloroacetates of demethylthiocolchicines and of N-acetylcolchinol; isothiocyanate of 9-deoxy-N-acetylcolchinolBOYE, O; GETAHUN, Z; GROVER, S et al.Journal of labelled compounds & radiopharmaceuticals. 1993, Vol 33, Num 4, pp 293-299, issn 0362-4803Article

Tubulin-guided dynamic combinatorial library of thiocolchicine—podophyllotoxin conjugatesCAPPELLETTI, Graziella; CARTELLI, Daniele; PERETTO, Bruno et al.Tetrahedron (Oxford. Print). 2011, Vol 67, Num 38, issn 0040-4020, 7191, 7354-7357 [5 p.]Article

3-demethoxy-3-glycosylaminothiocolchicines : Synthesis of a new class of putative muscle relaxant compoundsGELRNI, Maria Luisa; POCAR, Donato; JOHNSON, Francis et al.Journal of medicinal chemistry (Print). 2006, Vol 49, Num 18, pp 5571-5577, issn 0022-2623, 7 p.Article

An investigation of the 1251-radioiodination of colchicine for medical purposesEL-AZONY, K. M; EL-MOHTY, A. A; KILLA, H. M et al.Journal of labelled compounds & radiopharmaceuticals. 2009, Vol 52, Num 1-2, pp 1-5, issn 0362-4803, 5 p.Article

Tubulin polymerization inhibitors with a fluorinated phthalimide skeleton derived from thalidomideYANAGAWA, Tomonori; NOGUCHI, Tomomi; MIYACHI, Hiroyuki et al.Bioorganic & medicinal chemistry letters (Print). 2006, Vol 16, Num 18, pp 4748-4751, issn 0960-894X, 4 p.Article

NEW ALTERNATIVES TO OXIDATIVE PHENOLIC COUPLING IN NATURAL PRODUCTS TOTAL SYNTHESISEVANS DA; HART DJ; KOELSCH PM et al.1979; PURE APPL. CHEM.; GBR; DA. 1979; VOL. 51; NO 6; PP. 1285-1300; BIBL. 9 REF.Conference Paper

Phenylimino-10H-anthracen-9-ones as novel antimicrotubule agents—synthesis, antiproliferative activity and inhibition of tubulin polymerizationPRINZ, Helge; SCHMIDT, Peter; BÖHM, Konrad J et al.Bioorganic & medicinal chemistry. 2011, Vol 19, Num 14, pp 4183-4191, issn 0968-0896, 9 p.Article

Glycopeptide dendrimer colchicine conjugates targeting cancer cellsJOHANSSON, Emma M. V; DUBOIS, Joëlle; DARBRE, Tamis et al.Bioorganic & medicinal chemistry. 2010, Vol 18, Num 17, pp 6589-6597, issn 0968-0896, 9 p.Article

[4-(imidazol-1-yl)thiazol-2-yl]phenylamines. A novel class of highly potent colchicine site binding tubulin inhibitors : Synthesis and cytotoxic activity on selected human cancer cell linesMAHBOOBI, Siavosh; SELLMER, Andreas; HÖBCHER, Heymo et al.Journal of medicinal chemistry (Print). 2006, Vol 49, Num 19, pp 5769-5776, issn 0022-2623, 8 p.Article

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